Selective Androgen Receptor Modulators (SARMs) have become popular among fitness enthusiasts for their potential to enhance muscle growth and fat loss without many of the harsh side effects of traditional steroids. Among the most powerful of these compounds is S23, a SARM known for its potency and ability to significantly increase lean muscle mass. In this article, we’ll explore s23 dosage, half-life, side effects, results, and how S23 actually works to give you a complete understanding before you decide to buy S23 or use it in your fitness routine.

S23 is a non-steroidal selective androgen receptor modulator developed by GTx, Inc. It was originally designed as a potential male contraceptive because of its strong binding affinity to androgen receptors. Unlike anabolic steroids, S23 selectively targets muscle and bone tissues, minimizing unwanted hormonal imbalances. However, because of its high potency, S23 is often considered one of the most powerful SARMs currently available.
When discussing S23 dosage, it’s important to remember that S23 is still a research chemical and not approved for human use by the FDA. However, anecdotal reports from experienced users suggest a typical dosage range of 10–30 mg per day, often split into two doses due to its relatively short half-life.
It’s recommended to start low to assess tolerance. S23 is potent, and higher doses don’t always equal better results—they can increase the risk of side effects. Most users run S23 cycles for 6–8 weeks followed by a proper post-cycle therapy (PCT) to restore hormonal balance.
The s23 half life is estimated to be around 10–12 hours. This means it stays active in your body for roughly half a day, which is why many users split their doses—one in the morning and one in the evening—to maintain consistent levels in the bloodstream.
Because of its short half-life, missing a dose may reduce the compound’s effectiveness, so consistency is key when running an S23 cycle.
If you’re wondering how S23 works, it functions by binding to androgen receptors in muscle and bone tissue. This selective activation promotes protein synthesis, leading to increased muscle growth, enhanced strength, and improved endurance.
S23 also suppresses the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which can reduce natural testosterone levels. This is why PCT (Post Cycle Therapy) is strongly recommended after using S23 to help your body recover its natural hormone production.
In short, S23 works by mimicking many of the muscle-building effects of testosterone—without converting to estrogen or DHT, which are often responsible for side effects seen in steroid users.
While S23 is praised for its effectiveness, it’s also known for its strong suppression of natural testosterone. Some of the most reported s23 side effects include: